![]() ![]() However, there was a significant difference in favor of the transobturator approach when comparing the reduction in the number of post-operative urge-incontinence episodes (RP: 2.6 vs., TO 3.7, p: 0.047). When analyzing post-operative questionnaire there was a clear overall improvement with respect to the pre-operative scores in both techniques. Demographic variables and questionnaire scores were similar in both groups (Table no.1). Of these, 47.5% were randomized to TO and 52.5% to RP. Results: Two hundred and four women agreed to participate. After multivariate adjustment, sacrococcygeal curve depth and fibroid location within the true pelvis vs abdomen were not significantly associated with PFDI or UDI6 scores. UDI6 subscore was significantly associated with these factors as well as diuretic use (β=13.1, 95%CI 1.5-24.7 p=0.027). Asian race was significantly associated with lower PFDI score (β=-15.5, 95%CI -30.0-0.9 p=0.036) and African American race trended with higher PFDI scores (β=16.3, 95%CI -0.99-33.5 p=0.065). Kruskal-wallis rank test found no significant association between fibroid location on the uterus (anterior, posterior, fundal) or within the uterine wall (intramural, submucosal, subserosal, pedunculated) and total PFDI subscore or UDI6 subscore. Spearman’s correlation showed that depth of the sacroccygeal curve was significantly associated with PFDI ( r=0.116, p=0.027) while uterine volume ( p=0.19) and dominant fibroid volume ( p=0.21) were not associated with PFDI. Fibroid location (relative to bony landmarks) revealed two-thirds of patients had fibroids extending into the abdomen, while one-third had fibroids confined to the true pelvis ( p=0.016). Overall, 79.1% of women reported urinary frequency, 75.3% experienced genital discomfort, and 55.3% had urge incontinence. Results: Patients had a mean age of 43.9 years (SD 6.9), a median PFDI score of 72.7 (IQR 71.9), and a median UDI6 subscore of 29.1 (IQR 29.9) with a right-skewed, non-normal distribution. Urinary Incontinence (UI) Characteristics Institutional research ethics approval was obtained. To account for incomplete questionnaires, we recruited 105 subjects. We hypothesized that 25% of OAB patients would be categorized as having anxiety, versus 5% of LUTS-other patients, and sample size calculation indicated a need for 100 subjects. Significant confounders were included in a logistic regression analysis. Demographic variables included age, parity, menopausal status, hormone replacement, smoking, recreational drug use, alcohol consumption, caffeine intake, total daily fluid intake, post-void residual urine volume (PVR), depression, use of beta-blockers and anxiolytics, marital/partner status, post-secondary education (as a surrogate for socioeconomic status), and pre-existing anxiety diagnosis. ![]() A 2x2 contingency table was created, and a 2-tailed Fisher’s exact test was used to test the association between OAB and anxiety. GAD-7 scores categorized patients as having anxiety using a cut-off of greater than or equal to 14. ![]() Based on ICIQ-OAB scores greater than or equal to 28, patients were dichotomized as having OAB versus LUTS-other (typically patients referred for stress urinary incontinence). Methods: Ambulatory clinic patients referred to a tertiary urogynecology clinic for LUTS completed two questionnaires, (i) International Consultation on Incontinence Modular Questionnaire for Overactive Bladder (ICIQ-OAB), and (ii) Generalized Anxiety Disorder 7-Item Scale (GAD-7). ![]()
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